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Alkyne-PEG4-maleimide

Maleimide Alkine PEG4 (Tetraethylenglycol)
Artikel-Nr. Packungseinheit Preis Vorlaufzeit
2002-100mg 100 mg $150.00 Auf Lager
2002-1g 1 g $590.00 Auf Lager
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When proteins or other sensitive biomolecules need to be conjugated, polyethyleneglycol (PEG) linkers are a great choice. They provide hydrophilicity and maintain separation between conjugated molecules. This linker based on PEG4, has length of 14Å (1.4 nm). Heterobifunctional linkers carrying different reactive groups can be used to prepare cross-conjugates between different molecules.

Maleimide functional group is especially useful, because they can label proteins site specifically. Most proteins have only limited number of cysteine residues that selectively react with maleimides. Alkyne group can be then conjugated with azides in a selective copper-catalyzed process, CuAAc (copper-catalyzed alkyne azide cycloaddition).

Alkin-PEG4-maleimid, 2002-100mg
Alkin-PEG4-maleimid, 2002-100mg
Alkin-PEG4-maleimid, 2002-100mg
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Alkyne-PEG4-amine

A bifunctional linker molecule containing both terminal alkyne moiety for Click chemistry, and amine group. Contains a long hydrophilic PEG4 arm.

Alkinmaleimid

Maleimid-Reagenz zum Anfügen von Alkingruppen an cysteinhaltige Proteine, Peptide und andere Thiolgruppen tragende Moleküle

Iodo-PEG3-azide

Iodo PEG3 azide is a bifunctional linker with a highly reactive alkylative halogen functional group, and an azido group for Click chemistry / Staudinger ligation.

General properties

Appearance: yellow oil
Mass spec M+ increment: 311.3
Molecular weight: 311.33
CAS number: 1262681-30-0
Molecular formula: C15H21NO6
Solubility: good in water, DMF, DMSO
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 12 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.
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