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TAMRA maleimide, 6-isomer

TAMRA (TMR, Tetramethylrhodamin) Maleimide

Artikel-Nr.	Packungseinheit	Preis	Vorlaufzeit
18180	1 mg	$110	Auf Lager
28180	5 mg	$260	Auf Lager
48180	25 mg	$410	Auf Lager
58180	50 mg	$695	Auf Lager
68180	100 mg	$1190	Auf Lager

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TAMRA (also known as TMR or tetramethylrhodamine) is a xanthene dye that has been used as a fluorescent label for decades. Xanthene dyes are available as two isomers (called 5- and 6-isomers) that have almost identical fluorescent properties but need to be separated to avoid doubling and smearing of labeled product peaks or bands during chromatography or electrophoresis. This is a pure 6-isomer of TAMRA maleimide, which can be used to label proteins and peptides via thiol (SH) groups.

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Absorptions- und Emissionsspektren von 6-TAMRA

Empfohlenes Protokoll

Maleimid-Markierung von Proteinen und anderen thiolhaltigen Biomolekülen

Rechner

Lösungs- und Verdünnungsrechner

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TAMRA-Maleimid, 5-Isomer

Maleimid-Derivat von TAMRA (Tetramethylrhodamin) zur Markierung von Thiolgruppen. Reines 5-Isomer von TAMRA.

sulfo-Cyanine7.5 maleimide

sulfo-Cyanine7.5 is a highly hydrophilic near infrared dye for in vivo imaging. This maleimide derivative is useful for the labeling of thiol groups of proteins and peptides.

AF 488-Maleimid

AF 488 C6 Maleimid ist ein thiolreaktiver Farbstoff zur Markierung von Protein-SH-Gruppen.

General properties

Appearance:	dark colored solid
Mass spec M+ increment:	551.2
Molecular weight:	552.58
Molecular formula:	C₃₁H₂₈N₄O₆
Solubility:	good in DMSO, DMF
Quality control:	NMR ¹H, HPLC-MS (95%)
Storage conditions:	Storage: 12 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.
Sicherheitsdatenblatt:	herunterladen
	Product specifications

Spectral properties

Excitation/absorption maximum, nm:	541
ε, L⋅mol⁻¹⋅cm⁻¹:	84000
Emission maximum, nm:	567
Fluorescence quantum yield:	0.1
CF₂₆₀:	0.32
CF₂₈₀:	0.19

Zitierungen

Li, H.; Li, X.; Chen, L.; Li, B.; Dong, H.; Liu, H.; Yang, X.; Ueda, H.; Dong, J. Quench-Release-Based Fluorescent Immunosensor for the Rapid Detection of Tumor Necrosis Factor α. ACS Omega, 2021, 6(46), 31009–31016. doi: 10.1021/acsomega.1c03941
Mendez, A.S.; Ly, M.; González-Sánchez, A.M.; Hartenian, E.; Ingolia, N.T.; Cate, J.H.; Glaunsinger, B.A. The N-terminal domain of SARS-CoV-2 nsp1 plays key roles in suppression of cellular gene expression and preservation of viral gene expression. Cell Reports, 2021, 37(3), 109841. doi: 10.1016/j.celrep.2021.109841
Ast, J.; Arvaniti, A.; Fine, N. H. F.; Nasteska, D.; Ashford, F. B.; Stamataki, Z.; Koszegi, Z.; Bacon, A.; Jones, B. J.; Lucey, M. A.; Sasaki, S.; Brierley, D. I.; Hastoy, B.; Tomas, A.; D’Agostino, G.; Reimann, F.; Lynn, F. C.; Reissaus, C. A.; Linnemann, A. K.; D’Este, E.; Calebiro, D.; Trapp, S.; Johnsson, K.; Podewin, T.; Broichhagen, J.; Hodson, D. J. Super-Resolution Microscopy Compatible Fluorescent Probes Reveal Endogenous Glucagon-like Peptide-1 Receptor Distribution and Dynamics. Nature Communications, 2020, 11(1), 467. doi: 10.1038/s41467-020-14309-w
Sagert, L.; Hennig, F.; Thomas, C.; Tampé, R. A loop structure allows TAPBPR to exert its dual function as MHC I chaperone and peptide editor. eLife, 2020, 9, e55326. doi: 10.7554/eLife.55326

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This Product is offered and sold for research purposes only. It has not been tested for safety and efficacy in food, drug, medical device, cosmetic, commercial or any other use. Supply does not express or imply authorization to use for any other purpose, including, without limitation, in vitro diagnostic purposes, in the manufacture of food or pharmaceutical products, in medical devices or in cosmetic products.