Sulfo-Cyanine3 hydrazide
| Artikel-Nr. | Packungseinheit | Preis | Vorlaufzeit | Jetzt kaufen |
|---|---|---|---|---|
| 11370 | 1 mg | $110.00 | Auf Lager | |
| 21370 | 5 mg | $290.00 | Auf Lager | |
| 41370 | 25 mg |
$690.00
|
Auf Lager | |
| 51370 | 50 mg |
$1270.00
|
Auf Lager | |
| 61370 | 100 mg |
$1990.00
|
Auf Lager |
Sulfo-Cyanine3 is a sulfated derivative of Cyanine3 dye, well soluble in water because of two negatively charged sulfo groups in its structure. By its spectral characteristics, this yellow-orange fluorescent dye is an analog of Cy™3.
Hydrazides efficiently react with aldehydes and ketones resulting in hydrazones, so this compound can be used for conjugation with carbonyl derivatives of biomolecules.
The reaction runs in aqueous conditions, which is important when working with antibodies and proteins. Cys-diol groups in sugars in glycosylated proteins and antibodies can be oxidized into dialdehydes, and cysteine in proteins can be converted with enzymes to formyl glycerol (i. e. reactive groups for conjugation with Sulfo-Cyanine3 hydrazide). Carboxyl groups of aspartic and glutamic acids in proteins and peptides can be also conjugated with Sulfo-Cyanine3 hydrazide in the presence of activating agents: carbodiimide (EDAC) or methyl morpholine (DMTMM) derivatives.
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Cyanin-3-hydrazid
Cyanin-3-hydrazid ist ein carbonylreaktiver Fluoreszenzfarbstoff für den Cyanin-3-Kanal.AF488 NHS ester
AF488 NHS ester, a bright, photostable and hydrophilic fluorescent dye for green channel.Sulfo-Cyanin-5.5-amin
Sulfo-Cyanin 5.5 ist ein hydrophiler Fernrot/NIR-Fluorophor mit guter Wasserlöslichkeit. Den Farbstoff zeichnet seine Helligkeit aufgrund des hervorragenden molaren Extinktionskoeffizienten aus. Dieses Aminderivat, das mit Elektrophilen reagiert, kann auch für Markierungen mittels enzymatischer Transaminierung eingesetzt werden.General properties
| Appearance: | dark red solid |
| Molecular weight: | 630.78 |
| CAS number: | 2144762-62-7 |
| Molecular formula: | C30H38N4O7S2 |
| IUPAC name: | 3H-Indolium, 2-[3-[1-(6-hydrazinyl-6-oxohexyl)-1,3-dihydro-3,3-dimethyl-5-sulfo-2H-indol-2-ylidene]-1-propen-1-yl]-1,3,3-trimethyl-5-sulfo-, inner salt |
| Solubility: | soluble in water, DMF, DMSO |
| Quality control: | NMR 1H, HPLC-MS (90%) |
| Storage conditions: | Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. |
| Sicherheitsdatenblatt:: | herunterladen |
| Product specifications |
Spectral properties
| Excitation/absorption maximum, nm: | 548 |
| ε, L⋅mol−1⋅cm−1: | 162000 |
| Emission maximum, nm: | 563 |
| Fluorescence quantum yield: | 0.1 |
| CF260: | 0.03 |
| CF280: | 0.06 |
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