sulfo-Cyanine7 TCO
| Artikel-Nr. | Packungseinheit | Preis | Vorlaufzeit | Jetzt kaufen |
|---|---|---|---|---|
| 153H0 | 1 mg |
$290.00
|
Auf Lager | |
| 253H0 | 5 mg |
$348.00
|
Auf Lager | |
| 353H0 | 10 mg |
$578.00
|
Auf Lager | |
| 453H0 | 25 mg |
$1220.00
|
Auf Lager |
sulfo-Cyanine7 TCO is a near-infrared (NIR) fluorescent dye functionalized with a trans-cyclooctene (TCO) moiety for rapid, catalyst-free bioorthogonal labeling via the inverse-electron-demand Diels-Alder (IEDDA) reaction with tetrazines.
The sulfo-Cyanine7 fluorophore provides strong absorption and emission in the NIR region (excitation at 750 nm, emission at 773 nm), enabling deep-tissue imaging, low cellular autofluorescence, and high signal-to-background ratios. Introduction of sulfonate groups renders the dye highly water-soluble and minimizes nonspecific interactions with cellular components, which is particularly advantageous for live-cell and in vivo applications.
The TCO group is a strained alkene that reacts extremely fast and selectively with tetrazine-modified biomolecules, enabling efficient labeling at low probe concentrations and short incubation times. This makes sulfo-Cyanine7 TCO well-suited for pretargeted imaging strategies, pulse-chase experiments, and dynamic studies of biomolecules.
Absorptions- und Emissionsspektren von Sulfo-Cyanin7
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General properties
| Appearance: | deep-blue crystals |
| Molecular weight: | 997.37 |
| CAS number: | 2129525-69-3 |
| Molecular formula: | C52H69KN4O9S2 |
| Solubility: | water, DMSO, DMF |
| Quality control: | NMR 1H and HPLC-MS (95+%) |
| Storage conditions: | 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Desiccate. Avoid prolonged exposure to light. |
| Sicherheitsdatenblatt: | herunterladen |
| Product specifications |
Spectral properties
| Excitation/absorption maximum, nm: | 750 |
| ε, L⋅mol−1⋅cm−1: | 240600 |
| Emission maximum, nm: | 773 |
| Fluorescence quantum yield: | 0.24 |
| CF260: | 0.04 |
| CF280: | 0.04 |
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