DSSO linker
| Artikel-Nr. | Packungseinheit | Preis | Vorlaufzeit | Jetzt kaufen |
|---|---|---|---|---|
| 5196-100mg | 100 mg |
$189.00
|
Auf Lager |
The DSSO (Disuccinimidyl sulfoxide) linker is an MS-cleavable, homobifunctional crosslinker engineered for modern cross-linking mass spectrometry (XL-MS), used for high-resolution analysis of protein-protein interactions (PPIs) and structural topology.
The unique feature is a central sulfoxide group that undergoes predictable, collision-induced dissociation (CID) during tandem MS (MS/MS). This cleavage yields characteristic doublet peaks in the MS/MS spectrum. This distinct fragmentation signature enables unambiguous identification of cross-linked peptides and facilitates automated data processing, directly addressing the complexity of proteome-wide cross-linking studies.
DSSO provides robust, lysine-specific covalent stabilization of protein complexes, delivering precise, residue-level constraints for integrative structural modeling.
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General properties
| Appearance: | white powder |
| Molecular weight: | 388.35 |
| CAS number: | 1351828-03-9 |
| Molecular formula: | C14H16N2O9S |
| Solubility: | DMSO |
| Quality control: | NMR 1H and HPLC-ELSD (95+%) |
| Storage conditions: | 12 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Desiccate. |
| Sicherheitsdatenblatt: | herunterladen |
| Product specifications |
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