Orotic acid (1,3-15N2) monohydrate
| Artikel-Nr. | Packungseinheit | Preis | Vorlaufzeit | Jetzt kaufen |
|---|---|---|---|---|
| 5354-1mg | 1.0 mg |
$126
|
12 Tagen. |
Orotic acid-1,3-15N2 (monohydrate) is the orotic acid labeled with a stable isotope of nitrogen and is intended for use as an internal standard for the quantification of orotic acid by GC- or LC-MS.
Orotic acid (6-Carboxyuracil) is an intermediate compound in the biosynthetic pathway of pyrimidines (orotic acid is converted to UMP by UMP synthase), primarily sourced in the body through a series of enzymatic reactions involving carbamoyl phosphate synthase II. Its production is influenced by various factors such as positive feedback from 5-phosphoribosyl-1-pyrophosphate and negative feedback from uridine triphosphate. The measurement of urinary orotic acid is useful in confirming the diagnosis of hereditary metabolic diseases. Orotic acid is a marker for measurement in routine newborn screening for urea cycle disorders.
-monohydrate.svg "Struktur von Orotsäure-(1,3-15N2)-Monohydrat")
General properties
| Appearance: | beige solid |
| Molecular weight: | 176.10 |
| CAS number: | 147687-63-6 |
| Molecular formula: | C5H4(15N)2O4•H2O |
| IUPAC name: | 1,2,3,6-Tetrahydro-2,6-dioxo-4-pyrimidinecarboxylic Acid-15N2 Monohydrate |
| Solubility: | DMSO |
| Quality control: | NMR 1H and HPLC-MS (95+ %, N: 98+ %) |
| Storage conditions: | 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Desiccate. |
| Sicherheitsdatenblatt: | herunterladen |
| Product specifications |
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