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exo-BCN CE-phosphoramidite
| Artikel-Nr. | Packungseinheit | Preis | Vorlaufzeit | Jetzt kaufen |
|---|---|---|---|---|
| 4396-100mg | 100 mg | – | 12 Tagen. | |
| 4396-250mg | 250 mg |
$790
|
12 Tagen. | |
| 4396-1g | 1 g |
$2340
|
12 Tagen. | |
| 4396-5g | 5 g | auf Anfrage | 12 Tagen. |
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BCN-containing phosphoramidite is added at the 5’-terminus of an oligonucleotide. BCN is reactive both to azides (strain-promoted azyde-alkyne cycloaddition, SPAAC) and tetrazines (inverse electron demand Diels-Alder reaction, IEDDA).
Coupling time is standard, like for amidites of natural nucleosides. Exclude the dimethoxytrityl (DMT) removal step and use the Dmt-ON protocol after amidite coupling and oxidation.
Use standard conditions for deprotection and ammonia solution, or AMA mixture (ammonium hydroxide / 40% methylamine, 1:1).
General properties
| Appearance: | yellowish oil |
| Mass spec M+ increment: | 343.11 |
| Molecular weight: | 481.57 |
| Molecular formula: | C24H40N3O5P |
| Solubility: | good in acetonitrile |
| Quality control: | NMR 1H, NMR 31P (95 %) |
| Storage conditions: | 12 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Desiccate. |
| Sicherheitsdatenblatt: | herunterladen |
| Product specifications |
This Product is offered and sold for research purposes only. It has not been tested for safety and efficacy in food, drug, medical device, cosmetic, commercial or any other use. Supply does not express or imply authorization to use for any other purpose, including, without limitation, in vitro diagnostic purposes, in the manufacture of food or pharmaceutical products, in medical devices or in cosmetic products.
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