Creatinine-d3
| Artikel-Nr. | Packungseinheit | Preis | Vorlaufzeit | Jetzt kaufen |
|---|---|---|---|---|
| 5779-1mg | 1.0 mg |
$95.00
|
Auf Lager |
Creatinine is synthesized in the liver, kidneys, and pancreas, transported to muscle and brain tissue, where it is phosphorylated to phosphocreatine, while free creatine in muscle undergoes non-enzymatic conversion to creatinine. Creatinine levels in blood and urine serve as a key marker for estimating glomerular filtration rate. A persistent increase in blood creatinine indicates the development of renal impairment. Creatinine concentration is also used in screening for chronic conditions such as diabetes mellitus, hypertension, and heart failure. Urinary creatinine measurement is essential for clearance calculations and for diagnosing tubular disorders, particularly Fanconi syndrome.
Because creatinine-d3 is chemically identical to its unlabeled counterpart, it exhibits identical behavior during extraction, chromatography, and ionization. This makes it an optimal internal standard for pharmacokinetic, biochemical, and in vitro clinical laboratory assays.
It is used as an internal standard for the quantitative determination of creatinine by LC-MS/MS.
General properties
| Appearance: | white powder |
| Molecular weight: | 116.14 |
| CAS number: | 143827-20-7 |
| Molecular formula: | C4H4D3N3O |
| Quality control: | NMR 1H and HPLC-MS (95+ %, D: 98+ %) |
| Storage conditions: | 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Desiccate. |
| Sicherheitsdatenblatt: | herunterladen |
| Product specifications |
Ihr Warenkorb ist leer
$ 
