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2′-Deoxyadenosine-d2

Artikel-Nr.	Packungseinheit	Preis	Vorlaufzeit	Jetzt kaufen
4892-1mg	1 mg	$44.00	12 Tagen. (3er-Pack Stück)

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2′-Deoxyadenosine-(ribose-5,5-d2) is a deuterated form of the nucleoside 2′-deoxyadenosine and is intended for use as an internal standard for the quantification of deoxyadenosine by LC-MS/MS. Deoxyadenosine is a nucleoside that is converted to deoxyinosine by the enzyme adenosine deaminase and is a good marker of Adenosine deaminase (ADA) deficiency. Screening specific for ADA deficiency can be performed by detection of elevated levels of adenosine (Ado) and deoxyadenosine (dAdo) by tandem mass spectrometry. The ADA deficiency phenotypic spectrum includes typical early-onset severe combined immunodeficiency (ADA-SCID), diagnosed in infancy (about 80% of individuals), and less severe delayed or late-onset combined immunodeficiency (ADA-CID), diagnosed in older children and adults.

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Adenosine-d2

Adenosine-d2 is the deuterium labeled Adenosine and intended for use as an internal standa…

General properties

Appearance:	white powder
Molecular weight:	253.26
Molecular formula:	C₁₀H₁₁D₂N₅O₃
Solubility:	in water
Quality control:	NMR ¹H and HPLC-MS (95+ %, D: 98+ %)
Storage conditions:	24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Desiccate.
Sicherheitsdatenblatt:	herunterladen
	Product specifications

This Product is offered and sold for research purposes only. It has not been tested for safety and efficacy in food, drug, medical device, cosmetic, commercial or any other use. Supply does not express or imply authorization to use for any other purpose, including, without limitation, in vitro diagnostic purposes, in the manufacture of food or pharmaceutical products, in medical devices or in cosmetic products.